DiscoveryProbe™ NF-κB Signaling Compound Library Plus
178个NF-κB抑制剂的集合,用于NF-κB信号通路研究
Featured Products of the Library
Catalog No. | Product Name | Summary | Targets | CAS Number | Smiles |
A4084 | Vorinostat (SAHA, MK0683) | HDAC inhibitor | HDAC | 149647-78-9 | C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO |
A4090 | JNJ-26481585 | Potent HDAC inhibitor | HDAC | 875320-29-9 | CN1C=C(C2=CC=CC=C21)CNCC3CCN(CC3)C4=NC=C(C=N4)C(=O)NO |
A4093 | ITF2357 (Givinostat) | HDAC inhibitor | HDAC | 732302-99-7 | CCN(CC)CC1=CC2=C(C=C(COC(NC3=CC=C(C(NO)=O)C=C3)=O)C=C2)C=C1.O.Cl |
A4101 | Tubastatin A | HDAC6 inhibitor,potent and selective | HDAC | 1252003-15-8 | CN(C1)CCC2=C1C3=C(N2CC4=CC=C(C(NO)=O)C=C4)C=CC=C3 |
A4104 | AR-42 (OSU-HDAC42) | HDAC inhibitor,novel and potent | HDAC | 935881-37-1 | CC(C)C(C1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)C(=O)NO |
B1585 | SC-514 | ATP-competitive IKK-2 inhibitor, orally active | IκB/IKK | 354812-17-2 | C1=CSC=C1C2=CC(=C(S2)C(=O)N)N |
B2069 | ZLN005 | transcriptional regulator of PGC-1α | PGC-1α | 49671-76-3 | CC(C)(C)C1=CC=C(C=C1)C2=NC3=CC=CC=C3N2 |
B4880 | WS6 | inducer of β cell proliferation | IκB/IKK | 1421227-53-3 | CN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)CC3=CC=C(C=C3)OC4=NC=NC(=C4)NC(=O)C5CC5)C(F)(F)F |