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Angiotensin 1/2 (1-8) amide
血管收缩剂
Background
The physiologically active peptide angiotensin-2 (angiotensin 1- 8) is yielded from angiotensin-1, a substrate of ACE (angiotensin converting enzyme), by removing a dipeptide.
Angiotensin 1/2 (1-8) amide (H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-amide) is a peptide analogue to angiotensin II that is used as a vasopressor agent in the treatment of certain types of shock and circulatory collapse. It is a potent vasoconstrictor and is used as a cardiac stimulant.
Fig 1. Formula of angiotensin (1-8).
Chemical Properties
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 1045.19 |
| Formula | C50H72N14O11 |
| Synonyms | H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-amide |
| Solubility | insoluble in EtOH; ≥104.5 mg/mL in DMSO; ≥47.6 mg/mL in H2O |
| SDF | Download SDF |
| Canonical SMILES | OC(C[C@H](N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@@H]([C@H](CC)C)C(N[C@H](C(N2[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N)=O)=O)CCC2)=O)CC4=CN=CN4)=O)=O)=O)=O)=O)=O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。 |
化学结构
