ZPBP Polyclonal Antibody

Applications

Tested Applications:

IP, ELISA

Species specificity:

human, mouse, rat

Positive IP detected in:

mouse testis tissue

Recommended dilution:

IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB

Product Information

Source:

Rabbit

Purification method:

Antigen affinity purification

Isotype:

IgG

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:

ZPBP fusion protein Ag8585

Full name:

zona pellucida binding protein

Calculated molecular weight:

351 aa, 40 kDa

Observed molecular weight:

34 kDa

Gene symbol

ZPBP

Synonyms

SP38, zona pellucida binding protein, ZPBP, ZPBP1

Background

ZPBP (also known as ZPBP1), named for its binding to the oocyte zona pellucida, is a spermatid and spermatozoon protein that localizes to the acrosome. ZPBP may be implicated in gamete interaction during fertilization. It has been reported that absence of ZPBP1 prevents acrosome compaction and leads to acrosome fragmentation and sterility in male mice